Animal Models in Toxicology, Second Edition (Drug and - download pdf or read online

By Shayne C. Gad

ISBN-10: 0824754077

ISBN-13: 9780824754075

Reflecting greater than a decade’s worthy of adjustments, Animal versions in Toxicology, moment variation is a pragmatic advisor to the typical statistical difficulties encountered in toxicology and the methodologies which are to be had to unravel them. The booklet offers a old evaluation of using animal types and an outline of extensive issues of metabolism and relevance utilized in toxicology. person chapters overlaying the 8 significant species utilized in toxicology and experimental biology shape the middle of the ebook. With contributions from specialists in toxicology, toxicological pathology, and species-specific metabolism, every one of those chapters supply a good introductory “course” besides counsel to the literature for extra unique realizing.

The publication is going directly to make the case for quite a number species now not standard for protection review reports yet that can offer necessary substitute versions for a few particular endpoints. The bankruptcy authors talk about precise issues concerning the review and interpretation of the medical pathology of the 8 significant version species in addition to find out how to pick out a version species and the way to extrapolate the consequences to people. They aspect capability pitfalls and events that reason both human or version to be considerably extra delicate than the opposite or absolutely beside the point to one another. The booklet concludes with an outline of the more and more advanced legislation and laws that govern how laboratory animals are got, maintained, and applied, and an appendix that gives a brief advisor to advertisement resources of laboratory animals.

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Animal Models in Toxicology, Second Edition (Drug and Chemical Toxicology) by Shayne C. Gad


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